Nasal Delivery of Vaccines

EPC | OptiNose

Recently nasal delivery of vaccines has emerged as an attractive alternative to injection. Nasal vaccination elicits a local immune response and protection in addition to the systemic response. The mucosal immune response is rapid and nasal vaccines may induce protection in distant mucosal sites in the gut and uro-gentital tract as well. Proper formulation and adequate distribution to the nasal mucosa are essential for the efficiency and safety of mucosal vaccines. The complex nasal geometry represents a major challenge for efficient intranasal vaccination. Current delivery devices may prove inadequate to meet the future requirements for safe and reliable nasal vaccination. With permission from Pharmaceutical Manufacturing and Packing Sourcer.